Case Cohort Study

Definition

In a case-cohort study, cases are defined as those participants of the cohort who developed the disease of interest, but controls are identified before the cases develop. This means that controls are randomly chosen from all cohort participants regardless of whether they have the disease of interest or not, and that baseline data can be collected early in the study.

Case-cohort studies are very similar to nested case-control studies . The main difference between a nested case-control