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Acrogeria
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Acrogeria
Synonym(s)
Gottron's syndrome
Definition
Premature aging of the skin, predominately affecting the distal extremities, without other features of premature aging
Pathogenesis
Autosomal recessive inheritiance; may be related to type IV Ehlers-Danlos syndrome
Clinical manifestation
Dry, thin, wrinkled skin; most prominent over the distal