Acrodermatitis enteropathica

Synonym(s)

Acrodermatitis enteropathica; Danbolt-Closs syndrome; acrodermatitis enteropathica-like syndrome; transient symptomatic zinc deficiency; iatrogenic acrodermatitis enteropathica; zinc deficiency syndrome; zinc depletion syndrome; self-limiting acrodermatitis enteropathica

Definition

Autosomal recessive disorder with skin lesions, diarrhea, alopecia, photophobia, irritability, and failure to thrive

Pathogenesis

Deficient intestinal absorption of zinc from the small intestine

Clinical manifestation

Signs and symptoms appearing shortly after discontinuation of breast-feeding; red patches, scaly plaques, and eczematous skin that may evolve into crusted, vesiculobullous, erosive,