Acral lentiginous melanoma

Synonym(s)

Acral melanoma

Definition

Melanoma affecting the palms, soles, subungual, and periungual skin or the mucous membranes

Pathogenesis

Unknown

Clinical manifestation

Subungual melanoma: diffuse nail discoloration or a longitudinal pigmented band within the nail plate, with bleeding of pigment onto the nail fold (Hutchinson's sign)

Palmer or plantar melanoma: irregularly pigmented plaque with variable nodularity and late erosion or ulceration

Mucosal