> > Pristane-induced arthritis

This is the free portion of the full article. The full article is available to licensed users only.
How do I get access?

Pristane-induced arthritis


An animal model for rheumatoid arthritis, considered by some to be a joint specific model without extra-articular cartilage involvement. Disease expression is considered MHC-associated and T-cell dependent. Thought to be an optimal animal model for RA as the disease progression fulfils the RA criteria and has a chronic relapsing disease course.



Anti-oncostatin M antibodies have been used to neutralize PIA in CBA mice, in which 65% of PIA/CBA controls developed arthritis while in anti-OSM AB treated animals 0%