This is the free portion of the full article. The full article is available to licensed users only.
How do I get access?

Quassinoids: Chemistry and Novel Detection Techniques

Introduction
Structure: Quassinoids
Structure-Activity Relationship
Isolation, Detection, and Characterization
Isolation Methods
Separation/Purification Techniques
Structure Determination
Conclusion
References

Abstract

Natural products play a dominant role in pharmaceutical industry, providing resources for the discovery of new drug molecules. Quassinoids are degraded triterpenes reported from the members of the Simarouboidaea subfamily of Simaroubaceae. The importance of quassinoids as antiplasmodial, anticancer and anti-HIV compounds has revived interest in them as potential drug candidates. Its efficacy as combinatorial drug coupled with the structure-activity analysis has reclaimed novel structural leads for new drug development. Quassinoids are categorized into five distinct groups according to their basic skeleton, viz., C-18, C-19, C-20, C-22, and C-25. This present entry reviews the structure, structure-activity