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Molecular Aging Research

Definition

At the beginning of the last century the average life expectancy was about 37 years in the developed countries. Today life expectancy is approximately 70 years with a tendency to increase in the next decades. As early as the year 2050, approximately 25% of the population will have reached an age over 65. Consequently, as people are getting older, more and more will be affected by various age-associated disease including
  1. cardiovascular disorders,
  2. cerebrovascular diseases,
  3. malignant tumors and cancer
  4. chronic progressive neurodegenerative disorders.

In human aging an increase in the incidence of age-associated disorders is the cause of a decreased survival rate or an increased mortality. In addition to life threatening disorders that may lead to death in elderly people, a variety of age-associated changes lead to dysfunctions of different organs that include the brain. In particular, various neuropsychiatric disorders