Myosin Work and Motility: Mechanism
Myosins function by converting the chemical energy associated with ATP hydrolysis into force and directed motion. The goal of this review is to discuss the coupled chemical and mechanical cycles that allow this energy transduction to occur and to examine how this kinetic cycle is "tuned" by the various myosin classes to achieve distinct functions.
Myosin Structural Features
Although there are at least 35 distinct myosin classes implicated in a variety of cellular processes (Ordonitz and Kollmar 2007), all myosins share certain structural features, which are discussed in detail in "Myosin: Fundamental Properties and Structure." A brief overview is provided here.