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Textbook of Kanerva's Occupational Skin Diseases
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98 Skin Bioengineering
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98 Skin Bioengineering
Core Messages
- Clinical assessments of environmental dermatoses may be biased owing to their subjectivity and their wide interobserver variations.
- Skin bioinstrumentation aims at bringing accuracy, objectivity, reproducibility, sensitivity, and precision to clinical assessments.
- Occupational and environmental threats frequently alter the biological functions of the stratum corneum, and induce inflammation.
- Irritant and allergic contact dermatoses are conveniently explored using bioengineering methods.
- Transepidermal water loss and skin capacitance imaging represent two major dermometrological methods in occupational dermatology.
- Currently there is no bioengineering method elucidating the differential diagnosis between irritant and allergic contact dermatitis because the specificity of each method is limited.
- Due to their high sensitivity, the biometrological methods allow the severity rating of environmental dermatoses.