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Modeling and Simulation of Biosensors


Biosensors are analytical devices in which specific recognition of the chemical sub­stances is performed by biological material. The biological material that serves as recognition element is used in combination with a transducer. The transducer trans­forms concentration of substrate or product to electrical signal that is amplified and further processed. The biosensors may utilize enzymes, antibodies, nucleic acids, organelles, plant and animal tissue, whole organism or organs [1-3]. Biosensors contain­ing biological catalysts (enzymes) are called catalytical biosensors. These type biosensors are the most abundant, and they found the largest application in medicine, ecology, and environmental monitoring [4-5].

The action of catalytical biosensors is associated with substrate diffusion into biocatalytical membrane and it conversion to a product. The simulation of biosen­sors action includes solving the diffusion equations for substrate