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The DSM-IV-TR (2000) defines mood disorders in distinct groups including depressive and bipolar disorders. Major depressive disorder differs from bipolar disorder because there is no history of manic episodes, which is a defining characteristic of bipolar disorder .
In children, symptoms of a major depressive episode are shown through irritable or cranky moods and academic problems. Also, these symptoms are different from everyday irritability or frustration and are often comorbid with other childhood disorders, such as ADHD . Finally, depressive episodes emerge more during adolescence along with the onset of puberty [1, 4].