Addictive Disorder: Animal Models
Animal model: Experimental preparation developed for studying a given phenomenon found in humans. It is at the basis of experimental medicine, with its two sides: physiology and pathology.
Vulnerability or frailty: A construct inherent to medical practice, for genetic or environmental reasons. It represents a biological state at the limits of homeostasis.
Current Concepts and State of Knowledge
Introduction: A Model of What?
In behavioral pathology and comparative psychiatry a precondition for an animal model is to be informed about what will be modeled. The poor awareness of the complexity of such human conditions is the origin of misunderstanding between clinicians and neurobiologists.