Definition and Characteristics
Enterocolitis, Necrotizing. Figure 1 A neonate with necrotizing enterocolitis. Note the necrotic bowel found at laparotomy.
Non-specific clinical features include lethargy, poor feeding, temperature instability, apnea, respiratory distress, and bradycardia . Other manifestations such as abdominal wall erythema, abdominal tenderness and guarding, shock, metabolic acidosis, and disseminated intravascular coagulopathy are seen in severe cases.
NEC most commonly presents in the first 2 weeks of life . The incidence is estimated to be 3 per 1,000 live births and 50 to100 per 1,000 in very low birthweight infants (<1,500 g) . The male to female