Allergic contact dermatitis; Contact hypersensitivity
Definition and Characteristics
Itchy skin reaction with erythema, edema and vesicles occurring at the site of penetration of chemicals in pre-sensitized individuals. In the chronic phase, increased epidermal thickness with scales and painful fissures are frequent.
Widely common disease in both professional and extraprofessional settings. Prevalence in general population varies dramatically depending on the source considered. It has been reported that 2-15% of individuals residing in industrialized countries are skin sensitized at least to one substance, but the general assumption is that prevalence is greatly underestimated.